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KMID : 0361020190620100568
Korean Journal of Otolaryngology - Head and Neck Surgery
2019 Volume.62 No. 10 p.568 ~ p.574
Paradoxical Response to Cold Dry Air Provocation according to the Season in Allergic Rhinitis Patients
Park Ki-Ik

Jang Tae-Young
Kim Sung-Hoon
Kim Ki-Nam
Kim Young-Hyo
Abstract
Background and Objectives: We investigated the seasonal variation of nonspecific hyperreactivity by performing the cold dry air (CDA) provocation test in both summer and winter in patients with rhinitis.

Subjects and Method: We performed the CDA provocation test in 57 patients with allergic rhinitis (AR) or non-allergic rhinitis (NAR). Depending on the season and the type of rhinitis, we divided patients into four groups (Summer AR group, n=17; Winter AR group, n=15; Summer NAR group, n=18 and Winter NAR group, n=7) and compared the changes in nasal symptoms, total nasal volume (TNV), and minimal cross-sectional area (MCA) measured by acoustic rhinometry after CDA provocation in each group.

Results: When the CDA provocation was performed for AR patients in summer, nasal symptoms improved slightly, which was significantly different from those shown in winter (Summer AR vs. Winter AR, p=0.012). In addition, there was a significant difference in symptom change between AR and NAR patients in the summer (Summer AR vs. Summer NAR, p=0.033). There was no significant difference in TNV or MCA changes after CDA provocation depending on the type of rhinitis and season (p£¾0.05).

Conclusion: When performing CDA provocation in AR patients in summer, the examiner should pay attention to the possible paradoxical response.
KEYWORD
Acoustic rhinometry, Allergic rhinitis, Nasal provocation tests
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